The first generation of tissue sampling to measure gene expression: harm to animals, easy to cause animal death; Large data errors and lack of detail; The experimental operation is tedious.
The second generation of small animal living imager: darkroom operation required; Animals must be anesthetized and injected with fluorescein; Frequent anesthesia makes it difficult to assess animal behavior.
Third generation Gene Observer: A single operation for long-term documentation; No fluorescein injections; The animals were free to move around without a darkroom during the recording; Can be uninterrupted long-term record (days to weeks).
The 2017 Nobel Prize in Physiology and Medicine was awarded to three American scientists, Jeffrey C.Hall, Michael Rosbash and Michael W. Young, for their “discovery of molecular mechanisms controlling circadian rhythms.”
In vivo real-time long-term observation; No discontinuous records of anesthesia/wakefulness/sleep/behavior; No fluorescein injections; Simultaneous recordings of multiple brain regions or animals without interference. Equipped with temperature control and respiration monitor, effectively ensure that small animals maintain normal physiological activities during imaging.
We have the world’s top imported laser light source, core components from various countries, a full set of optical components; 1-4 channel, for your flexible choice; Can be directly connected to the existing scientific research platform, our company has independent software and hardware.
